Evan FlodenEvan Floden
May 15, 2025

Seqera Compute - Managed, Optimized Compute for Scalable Bioinformatics

Today, we’re thrilled to announce the Public Preview of Seqera Compute — fully managed, optimized compute for scientists to run Nextflow pipelines and interactive analyses effortlessly. Built for scalability and security, Seqera Compute ensures a hassle-free Nextflow and interactive analysis experience, empowering teams to move faster, scale smarter, and do more — all without the infrastructure burden.

Infrastructure is slowing R&D

While generating data has never been easier, analyzing it at scale remains a major bottleneck for R&D teams. From setting up cloud infrastructure to managing unpredictable costs, scientists must navigate operational, technical, and organizational challenges just to get workflows up and running—often relying heavily on DevOps and IT teams. In addition, the complexity of modern compute demands specialized expertise, diverting technical teams from high-value initiatives and strategic projects.

The result? A fragmented, slow-moving analysis process that stalls innovation and delays critical insights.

Enter Seqera Compute: Optimization under a single product

Seqera Compute removes the infrastructure complexity, delivering a fully managed compute environment optimized for running pipelines and interactive analysis quickly, and at scale. This enables scientists to provision compute and launch Nextflow pipelines in minutes, without the need for manual configuration or DevOps support.

Simplified infrastructure - Seqera Compute automates environment setup, resource provisioning, and scaling, removing infrastructure blockers so teams can launch workflows instantly and focus fully on analysis, not DevOps.

Optimized cost performance - Intelligent resource management reduces inefficiencies in cloud computing, optimizes job execution, and ensures you only pay for what you use. Teams benefit from faster runs, lower costs, and zero infrastructure maintenance.

Built for bioinformatics - Purpose-built for scientific analysis, Seqera Compute minimizes data movement and provides direct access to performance and troubleshooting metrics, enabling faster deployment, easier iteration, and quicker paths from data to discovery.

More flexibility for teams

Seqera Compute isn’t just a powerful default compute option, it’s another way we’re simplifying management and scalability while giving teams more choice. Whether used as the sole CE or alongside self-managed options, Seqera Compute helps reduce the management footprint without removing it entirely. This enables teams to focus on the compute that matters most. Seqera Compute empowers users to scale smarter, manage less, and tailor infrastructure to their evolving research needs.

Configuring a CE vs. Seqera Compute

Before Seqera Compute, launching pipelines meant first setting up a Seqera Platform CE, such as AWS Batch, to enable Seqera to submit tasks. This involves providing credentials, setting up storage and access permissions, enabling key services like Wave and Fusion, and specifying configuration details such as config mode, provisioning model, and resource limits like max CPUs:


While this level of control works well for teams with cloud expertise, others may prefer a ready-to-use compute solution that removes manual setup and complexity. Enter Seqera Compute: pipeline execution without the infrastructure overhead.

Key benefits of Seqera Compute

  • Hassle-free pipeline execution: Quickly launch Nextflow pipelines in fully managed, secure environments. Seqera Compute handles provisioning, scaling, and infrastructure, so teams don’t have to.
  • Optimized performance and lower costs: Seqera Compute fine-tunes every run with intelligent instance selection and optimized job execution, reducing inefficiencies in systems like AWS Batch and helping teams do more with less.
  • Accelerated time-to-value: Immediate access to compute eliminates delays, helping researchers analyze data faster and iterate more quickly.
  • Team autonomy without DevOps overhead: Scientists and bioinformaticians can run and manage pipelines without relying on IT or DevOps, unlocking productivity across R&D.
  • Cost control, without surprises: Pay for what you use, not what you provision. Seqera Compute dynamically scales with your workloads and offers a clear, predictable pricing model—eliminating waste and billing surprises.
  • Built-in security and maintenance: Run pipelines in secure, isolated environments with no shared infrastructure. Seqera Compute ensures data privacy and system reliability so teams can focus on research with confidence.

Interested in learning more?

Seqera Compute brings together everything teams need to run bioinformatics pipelines at scale: quickly, efficiently, and without infrastructure complexity. By removing DevOps overhead and optimizing for cost and performance, Seqera Compute makes large-scale data analysis more accessible, helping teams focus on what matters most: generating insights and accelerating discovery.

💡Visit the Seqera Compute product page for more details on features, benefits, and how to get started.