
CREA Selects Nextflow to Run Collaborative Genomics Analysis in Microsoft Azure
Read the full case studyAim
Conduct large-scale, reproducible bioinformatics analyses of genome data. Develop new varieties of crops to meet the rapid pace of climate change.Challenges
- →Managing access to infrastructure and bioinformatics tools across research divisions
- →Lack of standardization of analysis methods and tools makes reproducibility difficult
- →Inability to easily and securely share research, tools, and workflows hinders collaboration.
allocated just in time to support our specific research needs, dramatically
improving productivity.
— Luigi Cattivelli, Director, CREA-GB
Solution

Nextflow
Enabled highly efficient parallel execution and scaling of genomics analyses.
nf-core
Ensured reproducibility through peer-reviewed, standardized omics Nextflow pipelines.
Microsoft Azure
Easy access to scalable cloud resources, without needing to manage infrastructure on-premises.
Results
CREA, with its Research Centre for Genomics and Bioinformatics (CREA-GB) has been leading an effort to standardize genomics analysis by leveraging Nextflow pipelines in Microsoft Azure. By utilizing peer-reviewed, community-curated nf-core pipelines and Microsoft Azure, CREA has improved efficiency, collaboration, and reproducibility in their research. They have also established a shared infrastructure that serves as a model for all CREA research teams.
- →Reduced turnaround time from days to hours
- →Optimized resource usage and cost-savings
- →Enhanced research productivity
- →Improved cross-team collaboration
- →Reproducible genomics analysis at scale
- →Accelerated internal and external sharing of genomics procedures
Opportunity
Democratize bioinformatics tools
Provide every CREA scientist with the best bioinformatics tools, regardless of their local facilitieS.
Faster research
Accelerate the research flow from data analysis to real products.
Greater impact on plant breeding
Support the release of advanced varieties in many crops.
About
CREA is the leading Italian research organization entirely dedicated to the agri-food supply chains under the supervision of the Ministry of Agriculture, Food Sovereignty and Forests. The Centre for Genomics and Bioinformatics (CREA-GB) studies crop plant genomes and their interaction with the environment. CREA's scientific activity covers agricultural crops, livestock, fishery, forestry, agro-industry, food science, and socio-economics. In particular, CREA focuses on twenty-first-century challenges related to food production sustainability, following the principles of the circular, bio-based economy through a multidisciplinary approach that includes innovation transfer.
To learn more, visit https://www.crea.gov.it/en/about-crea