BioSkryb Scales Single-Cell Genomics with Seqera to Deliver Clinical Impact at Industry-Leading Costs

Aim

Enhance understanding of gene-disease relationships, accelerate the path from data to insights at industry-leading costs, and drive faster drug discovery through increased sample throughput.

Challenges

Single-cell omics data can provide crucial insights into cell-by-cell variability from small cellular populations, which can help us better understand disease mechanisms and inform treatment strategies. With next-generation single-cell technologies, BioSkryb Genomics are enabling researchers to get a complete multi-omic view of the cellular ecosystem via the high-precision analyses of individual cells, with the aim of transforming biological discovery and disease management. However, processing multi-omic data of thousands of cells is time-consuming, costly and biologically complex, which becomes unmanageable as data volumes surge.

Solution

• Nextflow: Powering BaseJumper bioinformatics platform for internal and external customers.
• MultiQC: Enabling quality control, metadata reporting and visualization of results.
• Seqera Platform: Optimization of speed, reliability, and cost efficiency of custom-developed pipelines.

Results

With Seqera, BioSkryb were able to increase sample throughput to thousands of samples per day using the same compute, while reducing pipeline costs by 70% over 2 years, enabling researchers to get results quicker at industry-leading cost efficiency. This enabled BioSkryb to support requests and queues from dozens of customers simultaneously, streamlining data processing and enhancing overall efficiency.

Feature image credit: https://www.bioskryb.com/applications/