Aim
To support expanded on-premises sequencing of plasmids for research, Addgene needed to scale analysis and QC capacity rapidly while leveraging existing in-house developed scripts and toolsChallenges
- →Increasing volume of incoming materials.
- →Growing plasmid library.
- →Analysis requirements outgrowing capacity.
- →Need for automated end-to-end processing.
By scaling up Nextflow pipelines, we were able to achieve a 9-fold reduction in manual effort by simply consolidating and automating our workflow.
— Jason Niehaus, Director of Data Science at Addgene
Solution
Nextflow
Automate their plasmid sequencing and analysis pipelines.
nf-core
An extensive developer community and curated nf-core community pipelines.
Results
- →Faster runtimes, lower costs
- →Shorter cycle times
- →Increased productivity
- →Reuse existing scripts and tools
- →Seamless access to cloud resources
- →Automate multi-step processes
About
Addgene is a global, nonprofit repository that was created to help scientists share plasmids. Plasmids are DNA-based research reagents commonly used in the life sciences. When scientists publish research papers, they deposit their associated plasmids at Addgene. Then, when other scientists read the publication, they have easy access to the plasmids needed to conduct future experiments.
To learn more, visit https://www.addgene.org/
Ready to Scale Bioinformatics Operations with Confidence?